"Setting up a Biotechnology Business in Germany"
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S.E. Moroney; Journal of Biotechnology in Healthcare, 1997 April 7, 4(1): 67-75.
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No abstract available
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“Modern Antibody Technology: The Impact on Drug Development”
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S.E. Moroney and A. Plückthun; Ed. J. Knaeblein, Wiley-VCH Verlag, Modern Biopharmaceuticals - Vol. 3, 2005
ISBN: 3-527-31184-X
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No abstract available
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"Generation, engineering and production of human antibodies using HuCAL"
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R. Ostendorp, C. Frisch, M. Urban; Springer, Antibodies - Volume 2: Novel technologies and therapeutic use, 2004: 13-52; ISBN 0-306-48315-7 (v.2)
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No abstract available
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"Monoclonal antibodies from phage display libraries"
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M. Urban; Arzneimittel-Forschung, 2005, 55 (11): 694-695
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No abstract available
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"Generation and screening of the synthetic Human Combinatorial Antibody Library HuCAL GOLD"
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I. Klagge; Ed. Melvyn Little, Cambridge University Press, Recombinant Antibodies for Immunotherapy, 2009: 75-89
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No abstract available
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"Fully Synthetic Human Combinatorial Antibody Libraries (HuCAL®) Based on Modular Consensus Frameworks and CDRs Randomized with Trinucleotides"
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(Copyright 2000 by Academic Press)
A. Knappik, L. Ge, A. Honegger, P. Pack, M. Fischer, G. Wellnhofer, A. Hoess, J. Wölle, A. Plückthun, B. Virnekäs, Journal of Molecular Biology, 2000 Feb 11, 296 (1): 57-86.
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Abstract
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"Fully human, HLA-DR-specific monoclonal antibodies efficiently induce programmed death of malignant lymphoid cells"
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ZA. Nagy, B. Hubner, C. Lohning, R. Rauchenberger, S. Reiffert, E. Thomassen-Wolf, S. Zahn, S. Leyer, EM. Schier, A. Zahradnik, C. Brunner, K. Lobenwein, B. Rattel, M. Stanglmaier, M. Hallek, M. Wing, S. Anderson, M. Dunn, T. Kretzschmar, M. Tesar;
Nature Medicine, 2002 Aug, 8(8): 801-807
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Abstract
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"Efficacy of the fully human monoclonal antibody MOR102 (#5) against intercellular adhesion molecule 1 in the psoriasis-severe combined immunodeficient mouse model"
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W-H. Boehncke, F.R. Ochsendorf, S. Noll, M. Urban, A. Popp, D. Waldherr, J. Haunschild, T. Litzenburger; The British Journal of Dermatology, 2005 Nov, 153(4): 758-766. Epub 2005 Aug 11
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Abstract
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"Simultaneous metal chelate affinity purification and endotoxin clearance of recombinant antibody fragments"
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T. Zimmerman, C. Petit Frère, M. Satzger, M. Raba, M. Weisbach, K. Döhn, A. Popp, M. Donzeau; Elsevier, Journal of Immunological Methods, 2006 Jul 31, 314(1-2): 67-73. Epub 2006 Jun 22
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Abstract
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"Antibody discovery: phage display"
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T. Kretzschmar, T. von Rüden; Current Opinion in Biotechnology, 2002 Dec, 13(6): 598-602
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Abstract
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"In vitro affinity maturation of human GM-CSF antibodies by targeted CDR-diversification"
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S. Steidl, O. Ratsch, B. Brocks, M. Dürr, E. Thomassen-Wolf; Elsevier, Molecular Immunology, 2008 Nov, 46(1): 135-44. Epub 2008 Aug 21
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Abstract
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"Human combinatorial Fab library yielding specific and functional antibodies against the human fibroblast growth factor receptor 3"
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R. Rauchenberger, E. Borges, E. Thomassen-Wolf, E. Rom, R. Adar, Y. Yaniv, M. Malka, I. Chumakov, S. Kotzer, D. Resnitzky, A. Knappik A, S. Reiffert, J. Prassler, K. Jury, D. Waldherr, S. Bauer, T. Kretzschmar, A. Yayon, C. Rothe; The Journal of Biological Chemistry, 2003 Oct 3, 278(40): 38194-38205
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Abstract
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"Fab MOR03268 triggers absorption shift of a diagnostic dye via packaging in a solvent-shielded fab dimer interface"
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R. C. Hillig, S. Urlinger, J. Fanghänel, B. Brocks, C. Haenel, Y. Stark, D. Sülzle, D. I. Svergun, S. Baesler, G. Malawski, D. Moosmayer, A. Menrad, M. Schirner, K. Licha; Elsevier, Journal of Molecular Biology, 2008 Mar 14, 377(1): 206-19. Epub 2008 Jan 5
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Abstract
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"Crystallization and molecular-replacement solution of a diagnostic fluorescent dye in complex with a specific Fab fragment"
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R. C. Hillig, S. Baesler, S. Urlinger, Y. Stark, S. Bauer, V. Badock, M. Huber, I. Bahr, M. Schirner, K. Licha; Acta crystallographica. Section F, Structural Biology and Crystallization Communications, 2007 Mar 1, 63(Pt 3): 217-23. Epub 2007 Feb 23
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Abstract
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"Improved bivalent miniantibodies, with identical avidity as whole antibodies, produced by high cell density fermentation of Eschericia coli"
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P. Pack, M. Kujau, V. Schroeckh, U. Knupfer, R. Wenderoth, D. Riesenberg, A. Plückthun; BIO/TECHNOLOGY, 1993 Nov, 11(11): 1271-1277
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Abstract
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"Protein microarrays for antibody profiling: Specificity and affinity determination on a chip"
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O. Poetz, R. Ostendorp, B. Brocks, J.M. Schwenk, D. Stoll, T.O. Joos, M.F. Templin; Proteomics, 2005 Jun, 5(9): 2402–2411
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Abstract
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"Multivalent antibody fragments with high functional affinity for a tumor-associated carbohydrate antigen"
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M. Rheinnecker, C. Hardt, L.L. Ilag, P. Kufer, R. Gruber, A. Hoess, A. Lupas,
C. Rottenberger, A. Plückthun, P. Pack; The Journal of Immunology, 1996 Oct 1, 157(7): 2989-2997
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Abstract
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"Bypassing hybridoma technology: HLA-C reactive human single-chain antibody fragments (scFv) derived from a synthetic phage display library (HuCAL®) and their potential to discriminate HLA class I specificities"
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M. Marget, B.B. Sharma, M. Tesar, T. Kretzschmar, S. Jenisch, E. Westphal, P. Davarnia, E. Weiss, M. Ulbrecht, D. Kabelitz, M. Krönke; Tissue Antigens, 2000, 56: 1-9
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Abstract
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"In vitro affinity maturation of HuCAL antibodies: complementarity determining region exchange and RapMAT technology"
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J. Prassler, S. Steidl, S. Urlinger; Future Medicine, Immunotherapy, 2009 Jul, 1(4): 571-583
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Abstract
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"Picomolar affinity antibodies from a fully synthetic naive library selected and evolved by ribosome display"
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J. Hanes, C. Schaffitzel, A. Knappik, A. Plückthun; Nature Biotechnology, 2000 Dec, 18(12): 1287-1292
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Abstract
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"Antifibrotic effects of a tissue inhibitor of metalloproteinase-1 antibody on established liver fibrosis in rats"
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CJ. Parsons, BU. Bradford, CQ. Pan, E. Cheung, M. Schauer, A. Knorr, B. Krebs, S. Kraft, S. Zahn, B. Brocks, N. Feirt, B. Mei, MS. Cho, R. Ramamoorthi, G. Roldan, P. Ng, P. Lum,
C. Hirth-Dietrich, A. Tomkinson, DA. Brenner; Hepatology, 2004 Nov, 40(5): 1106-15
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Abstract
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"The Human Combinatorial Antibody Library HuCAL GOLD combines diversification of all six CDRs according to the natural immune system with a novel display method for efficient selection of high-affinity antibodies"
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Christine Rothe, Stefanie Urlinger, Corinna Löhning, Josef Prassler, Yvonne Stark, Ute Jäger, Bernd Hubner, Michael Bardroff, Ingrid Pradel, Melanie Boss, Renate Bittlingmaier, Tschimegma Bataa, Christian Frisch, Bodo Brocks, Annemarie Honegger, Margit Urban; Elsevier, Journal of Molecular Biology, 2008 Feb 29, 376(4): 1182-200. Epub 2007 Dec 15
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Abstract
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"Kirrel2, a novel immunoglobulin superfamily gene expressed primarily in beta cells of the pancreatic islets"
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C. Sun, D. Kilburn, A. Lukashin, T. Crowell, H. Gardner, R. Brundiers, B. Diefenbach, J.P. Carulli; Genomics, 2003 Aug, 82(2): 130-142
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Abstract
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"Characterization of high-affinity antibodies by electrochemiluminescence-based equilibrium titration"
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C. Haenel, M. Satzger, D. Della Ducata, R. Ostendorp, B. Brocks; Analytical Biochemistry, 2005 Apr 1, 339(1): 182-184
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Abstract
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"From EST to IHC: human antibody pipeline for target research"
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C. Frisch, B. Brocks, R. Ostendorp, A. Hoess, T. von Rüden and T. Kretzschmar; Journal of Immunological Methods, 2003 Apr 1, 275(1-2): 203-212
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Abstract
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"Titration of Infective and Noninfective Ff Filamentous Bacteriophages Using a Monoclonal Antibody against g3p"
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C. Frisch, A. Knappik, M. Choidas, M. Tesar; BioTechniques, 2000 Jul, 29(1): 26-28
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Abstract
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"Trinucleotide phosphoramidites: ideal reagents for the synthesis of mixed oligonucleotides for random mutagenesis"
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B. Virnekäs, L. Ge, A. Plückthun, K.C. Schneider, G. Wellnhofer, S.E. Moroney; Nucleic Acids Research, 1994 Dec 25, 22(25): 5600-5607
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Abstract
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"High-throughput generation and engineering of recombinant human antibodies"
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B. Krebs, R. Rauchenberger, S. Reiffert, C. Rothe, M. Tesar, E. Thomassen, M. Cao, T. Dreier, D. Fischer, A. Hoss, L. Inge, A. Knappik, M. Marget, P. Pack, XQ. Meng, R. Schier, P. Sohlemann, J. Winter, J. Wolle, T. Kretzschmar; Journal of Immunological Methods, 2001 Aug 1, 254(1-2): 67-84
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Abstract
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"New protein engineering approaches to multivalent and bispecific antibody fragments"
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A. Plückthun, P. Pack; Immunotechnology, 1997 Jun, 3(2): 83-105
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Abstract
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