

Our Pipeline
An overview of the clinical studies on our own drug candidates and the most advanced clinical programs of our partners.
Our Pipeline
Latest Update: May 2022
MorphoSys' Clinical Programs
Selection of our Partners’ Clinical Programs

Gantenerumab is an anti-amyloid beta antibody developed for subcutaneous administration. It is being studied by Roche in several Phase 3 trials for the treatment of people living with Alzheimer’s disease and prevention of Alzheimer’s. Gantenerumab received Breakthrough Therapy Designation by the U.S. Food and Drug Administration (FDA).

Felzartamab is a therapeutic human monoclonal antibody directed against CD38, sublicensed to I-Mab for development in China, Hong Kong, Macao and Taiwan. I-Mab is evaluating the efficacy and safety of felzartamab in combination with dexamethasone (Phase 2) as well as in combination with lenalidomide (Phase 3) in relapsed/refractory multiple myeloma. I-Mab is also performing a Phase 1 study with felzartamab in Systemic Lupus Erythematosus (SLE).

Otilimab is an investigational human monoclonal antibody directed against GM-CSF (granulocyte-macrophage colony-stimulating factor) that is developed by GSK for the treatment of rheumatoid arthritis (Phase 3).

Ianalumab (VAY736) is an antibody directed against BAFF-R that is being investigated by Novartis in several indications including Sjögren’s syndrome, Autoimmune Hepatitis and Systemic Lupus Erythematosus (SLE). Ianalumab is currently in phase 2 clinical development and is expected to enter phase 3 clinical development in 2022 (Lupus Nephritis, Sjögren’s syndrome).

Abelacimab (MAA868) is an antibody directed against Factor XI that is being investigated by Anthos Therapeutics for the prevention of venous thromboembolism (VTE).

Setrusumab (BPS804) is an antibody directed against sclerostin that is currently being investigated by Ultragenyx and Mereo Biopharma in a phase 2/3 clinical study for the treatment of osteogenesis imperfecta.

NOV-8 (CMK389) is being investigated by Novartis for the treatment of pulmonary sarcoidosis (Phase 2) and severe atopic dermatitis (also Phase 2).

Bimagrumab is currently being investigated by Novartis and Versanis Bio in Phase 2 for the treatment of Type 2 diabetes.

NOV-9 (LKA651) is also currently being investigated by Novartis in Phase 2 for the treatment of diabetic eye diseases.

NOV-14 (CSJ117) is currently under investigation by Novartis for the treatment of Asthma (Phase 2) and chronic obstructive pulmonary disease (COPD; also currently in Phase 2).

MOR210 (TJ210) has been sublicensed to I-Mab Biopharma for development in China, Hong Kong, Macao, Taiwan and South Korea. It is currently being investigated for the treatment of relapsed or refractory advanced solid tumors (Phase 1).